Histone deacetylases 1 and 2 are expressed at distinct stages of neuro-glial development
نویسندگان
چکیده
منابع مشابه
Histone deacetylases 1 and 2 are phosphorylated at novel sites during varicella-zoster virus infection.
ORF66p, a virion-associated varicella-zoster virus (VZV) protein, is a member of a conserved Alphaherpesvirinae kinase family with homology to herpes simplex virus US3 kinase. Expression of ORF66p in cells infected with VZV or an adenovirus expressing only ORF66p results in hyperphosphorylation of histone deacetylase 1 (HDAC1) and HDAC2. Mapping studies reveal that phosphorylation is at a uniqu...
متن کاملSfrp-1 and sfrp-2 are expressed in overlapping and distinct domains during chick development
Secreted frizzled related proteins (Sfrps) are thought to bind and regulate Wnt activity through a cysteine rich domain that is highly similar to that of Frizzled receptors. To investigate possible roles for Sfrps in chick development, we have isolated partial cDNAs encoding Sfrp-1 and Sfrp-2 and have thoroughly characterized the expression patterns of both genes. Both sfrp-1 and sfrp-2 are exp...
متن کامل2-subunit gene: role of histone deacetylases
Zhang, Wenzheng, and Bruce C. Kone. NFB inhibits transcription of the H -K -ATPase 2-subunit gene: role of histone deacetylases. Am J Physiol Renal Physiol 283: F904–F911, 2002. First published July 9, 2002; 10.1152/ ajprenal.00156.2002.—The H -K -ATPase 2 (HK 2) gene plays a central role in potassium homeostasis, yet little is known about its transcriptional control. We recently demonstrated t...
متن کاملCORRIGENDUM: Adaptor protein complexes-1 and 3 are involved at distinct stages of flavivirus life-cycle
Intracellular protein trafficking pathways are hijacked by viruses at various stages of viral life-cycle. Heterotetrameric adaptor protein complexes (APs) mediate vesicular trafficking at distinct intracellular sites and are essential for maintaining the organellar homeostasis. In the present study, we studied the effect of AP-1 and AP-3 deficiency on flavivirus infection in cells functionally ...
متن کاملHistone deacetylases are required for amphibian tail and limb regeneration but not development
Amphibians such as Xenopus laevis and Ambystoma mexicanum are capable of whole structure regeneration. However, transcriptional control over these events is not well understood. Here, we investigate the role of histone deacetylase (HDAC) enzymes in regeneration using HDAC inhibitors. The class I/II HDAC inhibitor valproic acid (VPA) inhibits tail regeneration in embryos of the anuran amphibian ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Developmental Dynamics
سال: 2008
ISSN: 1058-8388,1097-0177
DOI: 10.1002/dvdy.21626